Moderna vs Pfizer: Is it OK to mix and match the updated COVID-19 booster shots?

As residents put together to roll up their sleeves for a 3rd, fourth or even fifth dose of COVID-19 vaccine, some could also be questioning: Do I would like to stay with the identical model, or is it secure to combine it up?

When it involves the new COVID-19 Omicron bivalent booster, the reply is, sure, you may combine and match.

You can get both the Pfizer-BioNTech or Moderna model, no matter which providing you beforehand obtained.

“The best booster for you is the one that you can get — either the Pfizer or the Moderna can be used, and they can be mixed or matched,” stated Dr. Robert Kim-Farley, epidemiologist and infectious illness professional on the UCLA Fielding School of Public Health. “If there’s shortages of one, you should not have hesitancy to take the other.”

Mixing and matching

Say an individual has obtained three doses of the Moderna shot. Should they stick with Moderna or combine it up with a Pfizer booster?

The impact on the physique’s immune system must be comparable both method, UC San Francisco infectious illness professional Dr. Peter Chin-Hong wrote in a tweet.

“It’s OK to mix and match Moderna and Pfizer,” Dr. Ralph Gonzales, affiliate dean for scientific innovation and chief innovation officer for UC San Francisco, stated at a campus city corridor final week. “I just got my Moderna two days ago and it was an interesting experience. I definitely felt a stronger response with the Moderna — having had Pfizer before — but either combinations are fine.”

The U.S. Food and Drug Administration really allowed mixing and matching of COVID-19 booster doses beginning final yr, after it allowed folks to get their first booster dose. Despite having the selection, although, lots of people ended up staying model loyal.

But others switched it up, both as a matter of choice, availability or advice. Many of those that initially obtained the single-dose Johnson & Johnson vaccine, as an illustration, opted for Pfizer or Moderna come booster time.

What is subsequent

When some folks — these age 50 and up and the immunocompromised — turned eligible for a second standard booster shot earlier this yr, some determined to go along with the opposite model. Dr. Robert Wachter, chair of the UC San Francisco Department of Medicine, in April determined to go along with Moderna for his fourth shot after three consecutive Pfizers.

“I saw it as a toss-up,” he tweeted on the time.

The up to date Omicron bivalent booster shot is on the market to these age 12 and up. Adults can select from both Pfizer or Moderna; adolescents age 12 to 17 are solely eligible for Pfizer.

L.A. County Public Health Director Barbara Ferrer stated there’s some expectation that the up to date booster might be obtainable for kids age 5 to 11 maybe as quickly as October.

Officials are urging folks to get the up to date booster, which they anticipate will cut back the chance of an infection. It’s known as a bivalent shot as a result of it’s designed to guard not solely in opposition to the unique coronavirus pressure, but additionally the newest Omicron subvariants which have dominated the nation this summer season, together with BA.5.

“The bivalent boosters provide protection against the subvariants that are currently circulating at the highest levels, and they’re going to be one of our best tools in planning for a safe, healthier and happier fall and winter holiday season,” Ferrer stated Thursday.

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